1. Psychological nursing: Before using exenatide, introduce the therapeutic effect and advantages of the drug to patients in detail, inform them of possible adverse reactions, teach them effective coping methods, eliminate their doubts about its safety and efficacy, and obtain their understanding and support. In addition, guide patients to learn to adjust their emotions, because maintaining a peaceful attitude has a positive significance for stabilizing blood sugar

2. Medication guidance: explain in detail the storage method, injection method and injection site of exenatide to patients during hospitalization. The unopened exenatide is stored in a refrigerator at 4 ℃. After use, it is stored at room temperature for 30 days. Even if it remains after 30 days, it should be discarded. It can be injected in the thigh, upper arm or abdomen, and the best part is the abdomen. The male is usually in the upper abdomen, and the female is in the lower abdomen, because it is convenient to operate here, the drug absorption is stable and reliable, and the fat is thick, so it is not easy to damage important tissues

Exenatide impurities is only used for subcutaneous injection. The injection site should be changed frequently and the local area should be strictly disinfected

Instruct patients to learn to observe adverse drug reactions, hypoglycemia and their treatment methods, and follow up regularly after discharge.

3. Observation and treatment of adverse drug reactions: when using exenatide, patients are encouraged to reduce their food intake, eat a small amount of food, chew slowly, and avoid flatulence; Reduce the intake of fat in food, avoid spicy and irritating food, and do not lie in bed immediately after meals. If nausea and vomiting occur, give anti emetic drugs, acupuncture and acupoint massage fmoc-osu according to the doctor's instructions to reduce gastrointestinal symptoms. At the same time, observe blood and urine amylase and renal function to prevent acute pancreatitis and renal failure. When the creatinine clearance rate of patients is less than 30 ml/min, it is not recommended to use. For patients with hyperlipidemia, special attention should be paid to the occurrence of pancreatitis

4. Regular blood glucose monitoring: encourage patients to participate in blood glucose monitoring and recording. For the elderly over 65 years old, blood glucose control should not be too strict; Avoid hunger and drinking, especially on an empty stomach; Blood sugar<5.5 mmol/L, unable to exercise. When combined with sulfonylurea drugs, the dosage of sulfonylurea drugs should be reduced; When used with insulin, the insulin injection dose should be accurate to avoid hypoglycemia. You can carry sugary food with you