The human skin has unique properties, most importantly as a physiochemical barrier.The conventional wisdom is that molecules above 500 cannot penetrate the skin, especially the cuticle.More research shows that this idea is not scientific, especially in dry skin and older skin.

And with new, more permeable peptides, even larger molecules can still penetrate well into the skin. The application of bioactive peptides in cosmetics industry has shown us a broader application prospect of peptides.Cost-benefit ratios are key in this field, and cost-breaking, peptide concentration and yield, stability and bioactivity performance will be key factors for the success of peptide products. 

Categories of cosmetically active peptides 1: Repair and improve skin quality The longitudinal section of the skin shows three layers: epidermis, dermis, and subcutaneous tissue.The epidermis and dermis are separated by the basal membrane, which is rich in extracellular matrix proteins (ECM), including collagen, epilugrin, laminin, fibrin, elastin, nestin, and heparan sulfate proteoglycan.ECM acts as a medium for cell-cell interactions connecting cells to organs.ECM guides cell proliferation and differentiation during cell proliferation and angiogenesis. 

The dermis produces a supportive matrix of collagen and elastin proteins involved in the formation of blood vessels and the nervous system.The largest group of fibrous ECM molecules is the collagen family, which contains more than 16 different types of collagen.Collagen in the dermal matrix is mainly composed of type I collagen (80-85%) and type III collagen (8-11%), both of which are fibrous or rod-shaped.These fibrous collagen molecules control skin firmness, and the fibrous collagen molecules are joined at the end to form microfibrils.

Collagen molecules cross over to form fibers that increase the strength and stability of skin connections. These active peptides can stimulate the production of collagen, elastin, glycoprotein and proteoglycan in the skin, which can be used as supplements for the loss of skin matrix.